Finding Ovarian Cancer

BRCAness: finding the Achilles heel in ovarian cancer.

Ovarian cancer is the leading cause of death among gynecological cancers. It exhibits great heterogeneity in tumor biology and treatment response. Germline mutations of DNA repair genes BRCA1/2 are the fundamental defects in hereditary ovarian cancer that expresses a distinct phenotype of high response rates to platinum agents, improved disease-free intervals and survival rates, and high-grade ...

Proteomics Analysis for Finding Serum Markers of Ovarian Cancer

A combination of peptide ligand library beads (PLLB) and 1D gel liquid chromatography-mass spectrometry/mass spectrometry (1DGel-LC-MS/MS) was employed to analyze serum samples from patients with ovarian cancer and from healthy controls. Proteomic analysis identified 1200 serum proteins, among which 57 proteins were upregulated and 10 were downregulated in the sera from cancer patients. Retinol...

ovarian hemangioma a rare pathologic finding

hemangioma of the ovary is reported in a 66 years old woman. vascular tumors of the female genital tract are rare, especially those of the ovaiy. most cases are discovered incidentally. the case presented here was missed clinically.

Giant ovarian cyst--an unusual finding.

A 16 year old unmarried girl presented with complaints of abdominal distension, vomiting, constipation, difficulty in breathing and restlessness. On examination abdomen was grossly distended with fluid thrill. Ultrasonographic examination revealed that there was a huge cystic collection with internal debris, multiple septations involving the whole abdomen and pelvis originating from right ovary...

Ovarian Metastasis in Endometriod Type Endometrial Cancer